Combinaisons de medicaments pour le traitement de neoplasmes

Combinations of drugs for the treatment of neoplasms

Abstract

L'invention concerne une méthode de traitement d'un patient présentant un cancer ou autre néoplasme, par administration au patient (i) d'un benzimidazole ou un métabolite ou analogue de ce dernier; et (ii) de la pentamidine ou un métabolite ou analogue de cette dernière, simultanément ou à 14 jours d'intervalle, dans des quantités suffisantes pour inhiber la croissance du néoplasme.
The invention features a method for treating a patient having a cancer or other neoplasm, by administering to the patient (i) a benzimidazole or a metabolite or analog thereof; and (ii) pentamidine or a metabolite or analog thereof simultaneously or within 14 days of each other in amounts sufficient to inhibit the growth of the neoplasm.

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Patent Citations (0)

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NO-Patent Citations (3)

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    DATABASE CAPLUS [Online] BORISY, A. ET AL.: 'Benzimidazole compound-pentamidine compound combinations for the treatment of neoplasms', XP002975593 Retrieved from STN Database accession no. 2004:60255 & WO 2004 006849 A2 22 January 2004
    DATABASE MEDLINE [Online] DEGER, E. ET AL.: 'A new therapeutic approach for the treatment of cystic echinococosis: percutaneous albendazole sulphoxide injection without reaspiration' Retrieved from STN Database accession no. 20102130 & AM. J. GASTROENTEROLOGY vol. 95, no. 1, January 2000, pages 248 - 254
    DATABASE USPATFULL [Online] BORISY ET AL.: 'Combinations of drugs (e.g. a benzimadozole and pentamidine) for treatment of neoplastic disorders', XP002975594 Retrieved from STN Database accession no. 2002:295212 & US 2002 165 261 A1 07 November 2002

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    WO-2004006849-A3June 03, 2004Alexis Borisy, Combinatorx Inc, Michael A Foley, Debra A Gaw, Curtis Keith, Brent R StockwellCombinations of drugs for the treatment of neoplasms
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